There are many types of fats. Among them, polyunsaturated fatty acids such as arachidonic acid are easily oxidized by reactive oxygen species and ultraviolet light. This oxidation reaction is the so-called "rust" of fats. Recently, it has become clear that oxidized lipids cause inflammatory reactions and cell death in vivo, and that they accumulate in many diseases such as age-related macular degeneration. In this seminar, I will introduce methods for detecting oxidized lipids, and also how to search for molecules that can inhibit the generation of oxidized lipids.

12:10 – 12:15　Introduction
Mami WAKABAYASHI, Associate Professor (Q-AOS Coodinator)

12:15 – 12:40 "Thinking about Fat “Rust””

Kenichi Yamada, Professor
(Department of Molecular Pathobiology, Faculty of Pharmaceutical Sciences,)

12:40 – 12:50 Q&A

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